One of the biggest rivalries in English football resumes on Sunday afternoon when Manchester United host Arsenal at Old Trafford.
Before the emergence of Chelsea and Manchester City this was often a fixture between the two title contenders, but there remains a desperation to win from both sides as they jostle for position in the table.
Van Gaal has been dealt a blow in his preparations for Sunday's match with the news that Wayne Rooney will miss out after picking up a knock against Palace last weekend.
Luke Shaw is also unavailable, but Angel di Maria and Robin van Persie are both set to return to the squad after recovering from their respective injury problems.
The Gunners are without one of their own forwards as former United striker Danny Welbeck continues his battle with a knee injury.
Aaron Ramsey has been unable to train for most of the week, but the Wales international should shake off a knock to start for the visitors once again.
Man Utd possible starting lineup:
De Gea, Valencia, Rojo, Smalling, Blind, Jones, Herrera, Mata, Fellaini, Young, Van Persie
Arsenal possible starting lineup:
Ospina, Bellerin, Mertesacker, Koscielny, Monreal, Cazorla, Coquelin, Ramsey, Ozil, Sanchez, Giroud
Tag : Premier League